Hydrocarbon molar water solubility predicts NMDA vs. GABA(A) receptor modulation

BACKGROUND: Many anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABA(A)) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar water solubility of a hydrocarbon could b...

Descripción completa

Detalles Bibliográficos
Autores principales: Brosnan, Robert J, Pham, Trung L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247779/
https://www.ncbi.nlm.nih.gov/pubmed/25410726
http://dx.doi.org/10.1186/2050-6511-15-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247779/
https://www.ncbi.nlm.nih.gov/pubmed/25410726
http://dx.doi.org/10.1186/2050-6511-15-62

Ejemplares similares