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Inhibition of Brain Swelling after Ischemia-Reperfusion by β-Adrenergic Antagonists: Correlation with Increased K(+) and Decreased Ca(2+) Concentrations in Extracellular Fluid
Infarct size and brain edema following ischemia/reperfusion are reduced by inhibitors of the Na(+), K(+), 2Cl(−), and water cotransporter NKCC1 and by β (1)-adrenoceptor antagonists. NKCC1 is a secondary active transporter, mainly localized in astrocytes, driven by transmembrane Na(+)/K(+) gradients...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247955/ https://www.ncbi.nlm.nih.gov/pubmed/25478577 http://dx.doi.org/10.1155/2014/873590 |