Plasma Gelsolin Levels Decrease in Diabetic State and Increase upon Treatment with F-Actin Depolymerizing Versions of Gelsolin

The study aims to map plasma gelsolin (pGSN) levels in diabetic humans and mice models of type II diabetes and to evaluate the efficacy of gelsolin therapy in improvement of diabetes in mice. We report that pGSN values decrease by a factor of 0.45 to 0.5 in the blood of type II diabetic humans and m...

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Detalles Bibliográficos
Autores principales: Khatri, Neeraj, Sagar, Amin, Peddada, Nagesh, Choudhary, Vikas, Chopra, Bhupinder Singh, Garg, Veena, Garg, Renu, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247973/
https://www.ncbi.nlm.nih.gov/pubmed/25478578
http://dx.doi.org/10.1155/2014/152075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247973/
https://www.ncbi.nlm.nih.gov/pubmed/25478578
http://dx.doi.org/10.1155/2014/152075

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