A DNA-based molecular probe for optically reporting cellular traction forces

We developed molecular tension probes (TPs) that report traction forces of adherent cells with high spatial resolution, can be linked to virtually any surface, and obviate monitoring deformations of elastic substrates. TPs consist of DNA hairpins conjugated to fluorophore-quencher pairs that unfold...

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Detalles Bibliográficos
Autores principales: Blakely, Brandon L., Dumelin, Christoph E., Trappmann, Britta, McGregor, Lynn M., Choi, Colin K., Anthony, Peter C., Duesterberg, Van K., Baker, Brendon M., Block, Steven M., Liu, David R., Chen, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247985/
https://www.ncbi.nlm.nih.gov/pubmed/25306545
http://dx.doi.org/10.1038/nmeth.3145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247985/
https://www.ncbi.nlm.nih.gov/pubmed/25306545
http://dx.doi.org/10.1038/nmeth.3145

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