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The immune synapse clears and excludes molecules above a size threshold

Natural killer cells assess target cell health via interactions at the immune synapse (IS) that facilitates signal integration and directed secretion. Here we test whether the IS also functions as a gasket. Quantitative fluorescence microscopy of nanometer-scale dextrans within synapses formed by va...

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Detalles Bibliográficos
Autores principales: Cartwright, Adam N. R., Griggs, Jeremy, Davis, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248232/
https://www.ncbi.nlm.nih.gov/pubmed/25407222
http://dx.doi.org/10.1038/ncomms6479