Differential spatial and structural organization of the X chromosome underlies dosage compensation in C. elegans

The adjustment of X-linked gene expression to the X chromosome copy number (dosage compensation [DC]) has been widely studied as a model of chromosome-wide gene regulation. In Caenorhabditis elegans, DC is achieved by twofold down-regulation of gene expression from both Xs in hermaphrodites. We show...

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Detalles Bibliográficos
Autores principales: Sharma, Rahul, Jost, Daniel, Kind, Jop, Gómez-Saldivar, Georgina, van Steensel, Bas, Askjaer, Peter, Vaillant, Cédric, Meister, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248290/
https://www.ncbi.nlm.nih.gov/pubmed/25452271
http://dx.doi.org/10.1101/gad.248864.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248290/
https://www.ncbi.nlm.nih.gov/pubmed/25452271
http://dx.doi.org/10.1101/gad.248864.114

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