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Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation
The male-specific lethal dosage compensation complex (MSL-DCC) selectively assembles on the X chromosome in Drosophila males and activates gene transcription by twofold through histone acetylation. An MSL recognition element (MRE) sequence motif nucleates the initial MSL association, but how it is r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248295/ https://www.ncbi.nlm.nih.gov/pubmed/25452275 http://dx.doi.org/10.1101/gad.250936.114 |