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Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis

We used mouse ENCODE data along with complementary data from other laboratories to study the dynamics of occupancy and the role in gene regulation of the transcription factor TAL1, a critical regulator of hematopoiesis, at multiple stages of hematopoietic differentiation. We combined ChIP-seq and RN...

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Detalles Bibliográficos
Autores principales: Wu, Weisheng, Morrissey, Christapher S., Keller, Cheryl A., Mishra, Tejaswini, Pimkin, Maxim, Blobel, Gerd A., Weiss, Mitchell J., Hardison, Ross C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248312/
https://www.ncbi.nlm.nih.gov/pubmed/25319994
http://dx.doi.org/10.1101/gr.164830.113