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Transposable element dynamics and PIWI regulation impacts lncRNA and gene expression diversity in Drosophila ovarian cell cultures

Piwi proteins and Piwi-interacting RNAs (piRNAs) repress transposable elements (TEs) from mobilizing in gonadal cells. To determine the spectrum of piRNA-regulated targets that may extend beyond TEs, we conducted a genome-wide survey for transcripts associated with PIWI and for transcripts affected...

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Detalles Bibliográficos
Autores principales: Sytnikova, Yuliya A., Rahman, Reazur, Chirn, Gung-wei, Clark, Josef P., Lau, Nelson C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248314/
https://www.ncbi.nlm.nih.gov/pubmed/25267525
http://dx.doi.org/10.1101/gr.178129.114