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Molecular dissection of the genetic mechanisms that underlie expression conservation in orthologous yeast ribosomal promoters

Recent studies have shown a surprising phenomenon, whereby orthologous regulatory regions from different species drive similar expression levels despite being highly diverged in sequence. Here, we investigated this phenomenon by genomically integrating hundreds of ribosomal protein (RP) promoters fr...

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Detalles Bibliográficos
Autores principales: Zeevi, Danny, Lubliner, Shai, Lotan-Pompan, Maya, Hodis, Eran, Vesterman, Rita, Weinberger, Adina, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248315/
https://www.ncbi.nlm.nih.gov/pubmed/25294245
http://dx.doi.org/10.1101/gr.179259.114