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Accounting for biases in riboprofiling data indicates a major role for proline in stalling translation

The recent advent of ribosome profiling—sequencing of short ribosome-bound fragments of mRNA—has offered an unprecedented opportunity to interrogate the sequence features responsible for modulating translational rates. Nevertheless, numerous analyses of the first riboprofiling data set have produced...

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Detalles Bibliográficos
Autores principales: Artieri, Carlo G., Fraser, Hunter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248317/
https://www.ncbi.nlm.nih.gov/pubmed/25294246
http://dx.doi.org/10.1101/gr.175893.114