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A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness
The relationship between genotype mutations and phenotype variations determines health in the short term and evolution over the long term, and it hinges on the action of mutations on fitness. A fundamental difficulty in determining this action, however, is that it depends on the unique context of ea...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248321/ https://www.ncbi.nlm.nih.gov/pubmed/25217195 http://dx.doi.org/10.1101/gr.176214.114 |