Assessment of the Potential of CDK2 Inhibitor NU6140 to Influence the Expression of Pluripotency Markers NANOG, OCT4, and SOX2 in 2102Ep and H9 Cells

As cyclin-dependent kinases (CDKs) regulate cell cycle progression and RNA transcription, CDKs are attractive targets for creating cancer cell treatments. In this study we investigated the effects of the small molecular agent NU6140 (inhibits CDK2 and cyclin A interaction) on human embryonic stem (h...

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Detalles Bibliográficos
Autores principales: Kallas, Ade, Pook, Martin, Trei, Annika, Maimets, Toivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248398/
https://www.ncbi.nlm.nih.gov/pubmed/25477962
http://dx.doi.org/10.1155/2014/280638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248398/
https://www.ncbi.nlm.nih.gov/pubmed/25477962
http://dx.doi.org/10.1155/2014/280638

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