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Immunization against a merozoite sheddase promotes multiple invasion of red blood cells and attenuates Plasmodium infection in mice

BACKGROUND: Subtilisin-like protease 2 (SUB2) is a conserved serine protease utilized by Plasmodium parasites as a surface sheddase required for successful merozoite invasion of host red blood cells and has been implicated in ookinete invasion of the mosquito midgut. To determine if SUB2 is a suitab...

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Detalles Bibliográficos
Autores principales: Smith, Ryan C, Colón-López, Daisy D, Bosch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248431/
https://www.ncbi.nlm.nih.gov/pubmed/25115675
http://dx.doi.org/10.1186/1475-2875-13-313