Lighter: fast and memory-efficient sequencing error correction without counting

Lighter is a fast, memory-efficient tool for correcting sequencing errors. Lighter avoids counting k-mers. Instead, it uses a pair of Bloom filters, one holding a sample of the input k-mers and the other holding k-mers likely to be correct. As long as the sampling fraction is adjusted in inverse pro...

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Detalles Bibliográficos
Autores principales: Song, Li, Florea, Liliana, Langmead, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248469/
https://www.ncbi.nlm.nih.gov/pubmed/25398208
http://dx.doi.org/10.1186/s13059-014-0509-9