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Acute Exposure to a Precursor of Advanced Glycation End Products Induces a Dual Effect on the Rat Pancreatic Islet Function

Aim. Chronic diseases are the leading cause of death worldwide. Advanced glycation end products, known as AGEs, are a major risk factor for diabetes onset and maintenance. Methylglyoxal (MG), a highly reactive metabolite of glucose, is a precursor for the generation of endogenous AGEs. Methods. In t...

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Detalles Bibliográficos
Autores principales: Elmhiri, Ghada, Barella, Luiz Felipe, Vieau, Didier, Camous, Sylvaine, Mathias, Paulo C. F., Abdennebi-Najar, Latifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248554/
https://www.ncbi.nlm.nih.gov/pubmed/25484898
http://dx.doi.org/10.1155/2014/378284