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Evaluation of Infective Property of Recombinant Prion Protein Amyloids in Cultured Cells Overexpressing Cellular Prion Protein

Misfolded isoform of prion protein (PrP), termed scrapie PrP (PrP(Sc)), tends to aggregate into various fibril forms. Previously, we reported various conditions that affect aggregation of recombinant PrP into amyloids. Because amyloidogenesis of PrP is closely associated with transmissible spongifor...

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Detalles Bibliográficos
Autores principales: Kim, Dae-Hwan, Lee, Hye-Mi, Ryou, Chongsuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248579/
https://www.ncbi.nlm.nih.gov/pubmed/25469058
http://dx.doi.org/10.3346/jkms.2014.29.12.1604