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Evaluation of Infective Property of Recombinant Prion Protein Amyloids in Cultured Cells Overexpressing Cellular Prion Protein
Misfolded isoform of prion protein (PrP), termed scrapie PrP (PrP(Sc)), tends to aggregate into various fibril forms. Previously, we reported various conditions that affect aggregation of recombinant PrP into amyloids. Because amyloidogenesis of PrP is closely associated with transmissible spongifor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248579/ https://www.ncbi.nlm.nih.gov/pubmed/25469058 http://dx.doi.org/10.3346/jkms.2014.29.12.1604 |