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Genome-wide redistribution of BRD4 binding sites in transformation resistant cells

Hutchinson–Gilford progeria syndrome (HGPS) patients do not develop cancer despite a significant accumulation of DNA damage in their cells. We have recently reported that HGPS cells are refractory to experimental oncogenic transformation and we identified the bromodomain-containing 4 protein (BRD4)...

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Detalles Bibliográficos
Autores principales: Si, Han, Scaffidi, Paola, Merchant, Anand, Cam, Maggie, Stahlberg, Eric, Misteli, Tom, Fernandez, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248721/
https://www.ncbi.nlm.nih.gov/pubmed/25478319
http://dx.doi.org/10.1016/j.gdata.2014.11.005