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Genome-wide redistribution of BRD4 binding sites in transformation resistant cells
Hutchinson–Gilford progeria syndrome (HGPS) patients do not develop cancer despite a significant accumulation of DNA damage in their cells. We have recently reported that HGPS cells are refractory to experimental oncogenic transformation and we identified the bromodomain-containing 4 protein (BRD4)...
Autores principales: | Si, Han, Scaffidi, Paola, Merchant, Anand, Cam, Maggie, Stahlberg, Eric, Misteli, Tom, Fernandez, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248721/ https://www.ncbi.nlm.nih.gov/pubmed/25478319 http://dx.doi.org/10.1016/j.gdata.2014.11.005 |
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