Effects of Dosage, Comorbidities, and Food on Isoniazid Pharmacokinetics in Peruvian Tuberculosis Patients

Poor response to tuberculosis (TB) therapy might be attributable to subtherapeutic levels in drug-compliant patients. Pharmacokinetic (PK) parameters can be affected by several factors, such as comorbidities or the interaction of TB drugs with food. This study aimed to determine the PK of isoniazid...

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Detalles Bibliográficos
Autores principales: Requena-Méndez, Ana, Davies, Geraint, Waterhouse, David, Ardrey, Alison, Jave, Oswaldo, López-Romero, Sonia Llanet, Ward, Stephen A., Moore, David A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249529/
https://www.ncbi.nlm.nih.gov/pubmed/25224007
http://dx.doi.org/10.1128/AAC.03258-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249529/
https://www.ncbi.nlm.nih.gov/pubmed/25224007
http://dx.doi.org/10.1128/AAC.03258-14

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