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Effects of Dosage, Comorbidities, and Food on Isoniazid Pharmacokinetics in Peruvian Tuberculosis Patients
Poor response to tuberculosis (TB) therapy might be attributable to subtherapeutic levels in drug-compliant patients. Pharmacokinetic (PK) parameters can be affected by several factors, such as comorbidities or the interaction of TB drugs with food. This study aimed to determine the PK of isoniazid...
Autores principales: | Requena-Méndez, Ana, Davies, Geraint, Waterhouse, David, Ardrey, Alison, Jave, Oswaldo, López-Romero, Sonia Llanet, Ward, Stephen A., Moore, David A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249529/ https://www.ncbi.nlm.nih.gov/pubmed/25224007 http://dx.doi.org/10.1128/AAC.03258-14 |
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