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Combined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcoma

BACKGROUND: Epithelioid sarcoma (EpS) is a high-grade malignant soft-tissue sarcoma characterized by local recurrences and distant metastases. Effective treatments for EpS have not been established and thus novel therapeutic approaches against EpS are urgently required. mTOR inhibitors exert antitum...

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Detalles Bibliográficos
Autores principales: Imura, Yoshinori, Yasui, Hirohiko, Outani, Hidetatsu, Wakamatsu, Toru, Hamada, Kenichiro, Nakai, Takaaki, Yamada, Shutaro, Myoui, Akira, Araki, Nobuhito, Ueda, Takafumi, Itoh, Kazuyuki, Yoshikawa, Hideki, Naka, Norifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249599/
https://www.ncbi.nlm.nih.gov/pubmed/25098767
http://dx.doi.org/10.1186/1476-4598-13-185