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Combined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcoma
BACKGROUND: Epithelioid sarcoma (EpS) is a high-grade malignant soft-tissue sarcoma characterized by local recurrences and distant metastases. Effective treatments for EpS have not been established and thus novel therapeutic approaches against EpS are urgently required. mTOR inhibitors exert antitum...
Autores principales: | Imura, Yoshinori, Yasui, Hirohiko, Outani, Hidetatsu, Wakamatsu, Toru, Hamada, Kenichiro, Nakai, Takaaki, Yamada, Shutaro, Myoui, Akira, Araki, Nobuhito, Ueda, Takafumi, Itoh, Kazuyuki, Yoshikawa, Hideki, Naka, Norifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249599/ https://www.ncbi.nlm.nih.gov/pubmed/25098767 http://dx.doi.org/10.1186/1476-4598-13-185 |
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