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Efficient production of single-chain fragment variable-based N-terminal trimerbodies in Pichia pastoris
BACKGROUND: Recombinant antibodies are highly successful in many different pathological conditions and currently enjoy overwhelming recognition of their potential. There are a wide variety of protein expression systems available, but almost all therapeutic antibodies are produced in mammalian cell l...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249718/ https://www.ncbi.nlm.nih.gov/pubmed/25112455 http://dx.doi.org/10.1186/s12934-014-0116-1 |