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Analysis of tumor- and stroma-supplied proteolytic networks reveals a brain metastasis-promoting role for cathepsin S

Metastasis remains the most common cause of death in most cancers, with limited therapies for combating disseminated disease. While the primary tumor microenvironment is an important regulator of cancer progression, it is less well understood how different tissue environments influence metastasis. W...

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Detalles Bibliográficos
Autores principales: Sevenich, Lisa, Bowman, Robert L., Mason, Steven D., Quail, Daniela F., Rapaport, Franck, Elie, Benelita T., Brogi, Edi, Brastianos, Priscilla K., Hahn, William C., Holsinger, Leslie J., Massagué, Joan, Leslie, Christina S., Joyce, Johanna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249762/
https://www.ncbi.nlm.nih.gov/pubmed/25086747
http://dx.doi.org/10.1038/ncb3011