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Expression of the GLI family genes is associated with tumor progression in advanced lung adenocarcinoma

BACKGROUND: The hedgehog (Hh) signaling pathway is aberrantly activated in various cancers. Expression of the GLI family of genes, which encode for transcriptional factors of the Hh pathway, has not been fully assessed in clinical samples of advanced lung adenocarcinoma. In this study, we retrospect...

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Detalles Bibliográficos
Autores principales: Ishikawa, Masashi, Sonobe, Makoto, Imamura, Naoto, Sowa, Terumasa, Shikuma, Kei, Date, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249769/
https://www.ncbi.nlm.nih.gov/pubmed/25103784
http://dx.doi.org/10.1186/1477-7819-12-253