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Expanding metabolic engineering algorithms using feasible space and shadow price constraint modules
While numerous computational methods have been developed that use genome-scale models to propose mutants for the purpose of metabolic engineering, they generally compare mutants based on a single criteria (e.g., production rate at a mutant׳s maximum growth rate). As such, these approaches remain lim...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249821/ https://www.ncbi.nlm.nih.gov/pubmed/25478320 http://dx.doi.org/10.1016/j.meteno.2014.06.001 |