Cargando…

A Novel CMKLR1 Small Molecule Antagonist Suppresses CNS Autoimmune Inflammatory Disease

Therapies that target leukocyte trafficking pathways can reduce disease activity and improve clinical outcomes in multiple sclerosis (MS). Experimental autoimmune encephalomyelitis (EAE) is a widely studied animal model that shares many clinical and histological features with MS. Chemokine-like rece...

Descripción completa

Detalles Bibliográficos
Autores principales: Graham, Kareem L., Zhang, Jian V., Lewén, Susanna, Burke, Thomas M., Dang, Ton, Zoudilova, Maria, Sobel, Raymond A., Butcher, Eugene C., Zabel, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249827/
https://www.ncbi.nlm.nih.gov/pubmed/25437209
http://dx.doi.org/10.1371/journal.pone.0112925