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Proteomic Profile and In Silico Analysis in Metastatic Melanoma with and without BRAF Mutation

INTRODUCTION: Selective inhibitors of BRAF, vemurafenib and dabrafenib are the standard of care for metastatic melanoma patients with BRAF V600, while chemotherapy continued to be widely used in BRAF wild type patients. MATERIALS AND METHODS: In order to discover novel candidate biomarkers predictiv...

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Detalles Bibliográficos
Autores principales: Garrisi, Vito Michele, Strippoli, Sabino, De Summa, Simona, Pinto, Rosamaria, Perrone, Antonella, Guida, Gabriella, Azzariti, Amalia, Guida, Michele, Stefania, Tommasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249853/
https://www.ncbi.nlm.nih.gov/pubmed/25437182
http://dx.doi.org/10.1371/journal.pone.0112025