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Generation of Recombination Activating Gene-1-Deficient Neonatal Piglets: A Model of T and B Cell Deficient Severe Combined Immune Deficiency

Although severe combined immune deficiency (SCID) is a very important research model for mice and SCID mice are widely used, there are only few reports describing the SCID pig models. Therefore, additional research in this area is needed. In this study, we describe the generation of Recombination ac...

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Detalles Bibliográficos
Autores principales: Ito, Tetsuya, Sendai, Yutaka, Yamazaki, Satoshi, Seki-Soma, Marie, Hirose, Kensuke, Watanabe, Motoo, Fukawa, Kazuo, Nakauchi, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249935/
https://www.ncbi.nlm.nih.gov/pubmed/25437445
http://dx.doi.org/10.1371/journal.pone.0113833