Hypermethylation of Cox5a Promoter Is Associated with Mitochondrial Dysfunction in Skeletal Muscle of High Fat Diet-Induced Insulin Resistant Rats

High-fat diet (HFD) is an environmental factor that contributes to the pathogenesis of obesity and type 2 diabetes. A number of genes influencing oxidative phosphorylation (OXPHOS) were found to be downregulated in skeletal muscle of humans and rats treated with HFD and have been implicated in mitoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Ying-ying, Liu, Yuan-yuan, Li, Jin, Su, Lei, Yu, Shuang, Zhu, Xiao-nan, Cao, Xiao-pei, Xiao, Hai-peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249960/
https://www.ncbi.nlm.nih.gov/pubmed/25436770
http://dx.doi.org/10.1371/journal.pone.0113784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249960/
https://www.ncbi.nlm.nih.gov/pubmed/25436770
http://dx.doi.org/10.1371/journal.pone.0113784

Ejemplares similares