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Hypermethylation of Cox5a Promoter Is Associated with Mitochondrial Dysfunction in Skeletal Muscle of High Fat Diet-Induced Insulin Resistant Rats

High-fat diet (HFD) is an environmental factor that contributes to the pathogenesis of obesity and type 2 diabetes. A number of genes influencing oxidative phosphorylation (OXPHOS) were found to be downregulated in skeletal muscle of humans and rats treated with HFD and have been implicated in mitoc...

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Detalles Bibliográficos
Autores principales:	Gong, Ying-ying, Liu, Yuan-yuan, Li, Jin, Su, Lei, Yu, Shuang, Zhu, Xiao-nan, Cao, Xiao-pei, Xiao, Hai-peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249960/ https://www.ncbi.nlm.nih.gov/pubmed/25436770 http://dx.doi.org/10.1371/journal.pone.0113784

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