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Selection of Intracellular Single-Domain Antibodies Targeting the HIV-1 Vpr Protein by Cytoplasmic Yeast Two-Hybrid System

The targeting of HIV-1 using antibodies is of high interest as molecular tools to better understand the biology of the virus or as a first step toward the design of new inhibitors targeting critical viral intracellular proteins. Small and highly stable llama-derived single-domain antibodies can ofte...

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Detalles Bibliográficos
Autores principales: Matz, Julie, Hérate, Cécile, Bouchet, Jérôme, Dusetti, Nelson, Gayet, Odile, Baty, Daniel, Benichou, Serge, Chames, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249982/
https://www.ncbi.nlm.nih.gov/pubmed/25436999
http://dx.doi.org/10.1371/journal.pone.0113729