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Regulation of PKM2 and Nrf2-ARE Pathway during Benzoquinone Induced Oxidative Stress in Yolk Sac Hematopoietic Stem Cells

Benzene is an occupational toxicant and an environmental pollutant that is able to induce the production of reactive oxygen species (ROS), causing oxidative stress and damages of the macromolecules in target cells, such as the hematopoietic stem cells. We had previously found that embryonic yolk sac...

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Detalles Bibliográficos
Autores principales: Zhu, Jie, Bi, Zhuoyue, Yang, Tan, Wang, Wei, Li, Zhen, Huang, Wenting, Wang, Liping, Zhang, Shaozun, Zhou, Yanfeng, Fan, Ningna, Bai, YuE, Song, Wentao, Wang, Chunhong, Wang, Hong, Bi, Yongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250037/
https://www.ncbi.nlm.nih.gov/pubmed/25437431
http://dx.doi.org/10.1371/journal.pone.0113733