Interface Matters: The Stiffness Route to Stability of a Thermophilic Tetrameric Malate Dehydrogenase

In this work we investigate by computational means the behavior of two orthologous bacterial proteins, a mesophilic and a thermophilic tetrameric malate dehydrogenase (MalDH), at different temperatures. Namely, we quantify how protein mechanical rigidity at different length- and time-scales correlat...

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Detalles Bibliográficos
Autores principales: Kalimeri, Maria, Girard, Eric, Madern, Dominique, Sterpone, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250060/
https://www.ncbi.nlm.nih.gov/pubmed/25437494
http://dx.doi.org/10.1371/journal.pone.0113895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250060/
https://www.ncbi.nlm.nih.gov/pubmed/25437494
http://dx.doi.org/10.1371/journal.pone.0113895

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