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DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage

Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility, and premature aging. It remains poorly understood how DNA damage responses function during organismal development and maintain tissue functionality when DNA damage accumulates w...

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Detalles Bibliográficos
Autores principales: Mueller, Michael M., Castells-Roca, Laia, Babu, Vipin, Ermolaeva, Maria A., Müller, Roman-Ulrich, Frommolt, Peter, Williams, Ashley B., Greiss, Sebastian, Schneider, Jennifer I., Benzing, Thomas, Schermer, Bernhard, Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250074/
https://www.ncbi.nlm.nih.gov/pubmed/25419847
http://dx.doi.org/10.1038/ncb3071