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DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage
Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility, and premature aging. It remains poorly understood how DNA damage responses function during organismal development and maintain tissue functionality when DNA damage accumulates w...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250074/ https://www.ncbi.nlm.nih.gov/pubmed/25419847 http://dx.doi.org/10.1038/ncb3071 |