Growth Inhibition of Head and Neck Squamous Cell Carcinoma Cells by sgRNA Targeting the Cyclin D1 mRNA Based on TRUE Gene Silencing

Head and neck squamous cell carcinoma (HNSCC) exhibits increased expression of cyclin D1 (CCND1). Previous studies have shown a correlation between poor prognosis of HNSCC and cyclin D1 overexpression. tRNase ZL-utilizing efficacious gene silencing (TRUE gene silencing) is one of the RNA-mediated ge...

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Detalles Bibliográficos
Autores principales: Iizuka, Satoshi, Oridate, Nobuhiko, Nashimoto, Masayuki, Fukuda, Satoshi, Tamura, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250192/
https://www.ncbi.nlm.nih.gov/pubmed/25437003
http://dx.doi.org/10.1371/journal.pone.0114121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250192/
https://www.ncbi.nlm.nih.gov/pubmed/25437003
http://dx.doi.org/10.1371/journal.pone.0114121

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