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DEPDC1B Coordinates De-adhesion Events and Cell-Cycle Progression at Mitosis

Cells entering mitosis become rounded, lose attachment to the substrate, and increase their cortical rigidity. Pivotal to these events is the dismantling of focal adhesions (FAs). How mitotic reshaping is linked to commitment to divide is unclear. Here, we show that DEPDC1B, a protein that accumulat...

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Detalles Bibliográficos
Autores principales: Marchesi, Stefano, Montani, Francesca, Deflorian, Gianluca, D’Antuono, Rocco, Cuomo, Alessandro, Bologna, Serena, Mazzoccoli, Carmela, Bonaldi, Tiziana, Di Fiore, Pier Paolo, Nicassio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250264/
https://www.ncbi.nlm.nih.gov/pubmed/25458010
http://dx.doi.org/10.1016/j.devcel.2014.09.009