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Autoregulatory Mechanism for Dynactin Control of Processive and Diffusive Dynein Transport

Dynactin is the longest known cytoplasmic dynein regulator, with roles in dynein recruitment to subcellular cargo and in stimulating processive dynein movement. The latter function was thought to involve the N-terminal microtubule binding region of the major dynactin polypeptide p150(Glued), though...

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Detalles Bibliográficos
Autores principales: Tripathy, Suvranta K., Weil, Sarah J., Chen, Chen, Anand, Preetha, Vallee, Richard B., Gross, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250405/
https://www.ncbi.nlm.nih.gov/pubmed/25419851
http://dx.doi.org/10.1038/ncb3063