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Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists

BACKGROUND: Endocrine disrupting chemicals (EDCs) are exogenous compounds that interfere with the endocrine system of vertebrates, often through direct or indirect interactions with nuclear receptor proteins. Estrogen receptors (ERs) are particularly important protein targets and many EDCs are ER bi...

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Detalles Bibliográficos
Autores principales: Ng, Hui Wen, Zhang, Wenqian, Shu, Mao, Luo, Heng, Ge, Weigong, Perkins, Roger, Tong, Weida, Hong, Huixiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251048/
https://www.ncbi.nlm.nih.gov/pubmed/25349983
http://dx.doi.org/10.1186/1471-2105-15-S11-S4