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Bioinformatic Dissecting of TP53 Regulation Pathway Underlying Butyrate-induced Histone Modification in Epigenetic Regulation
Butyrate affects cell proliferation, differentiation, and motility. Butyrate inhibits histone deacetylase (HDAC) activities and induces cell-cycle arrest and apoptosis. TP53 is one of the most active upstream regulators discovered by ingenuity pathways analysis (IPA) in our RNA-sequencing data set....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Libertas Academica
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251064/ https://www.ncbi.nlm.nih.gov/pubmed/25512709 http://dx.doi.org/10.4137/GEG.S14176 |