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Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders
A disruptive approach to therapeutic discovery and development is required in order to significantly improve the success rate of drug discovery for central nervous system (CNS) disorders. In this review, we first assess the key factors contributing to the frequent clinical failures for novel drugs....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251289/ https://www.ncbi.nlm.nih.gov/pubmed/25520658 http://dx.doi.org/10.3389/fphar.2014.00252 |