Length-dependent changes in contractile dynamics are blunted due to cardiac myosin binding protein-C ablation

Enhanced cardiac contractile function with increased sarcomere length (SL) is, in part, mediated by a decrease in the radial distance between myosin heads and actin. The radial disposition of myosin heads relative to actin is modulated by cardiac myosin binding protein-C (cMyBP-C), suggesting that c...

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Detalles Bibliográficos
Autores principales: Mamidi, Ranganath, Gresham, Kenneth S., Stelzer, Julian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251301/
https://www.ncbi.nlm.nih.gov/pubmed/25520665
http://dx.doi.org/10.3389/fphys.2014.00461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251301/
https://www.ncbi.nlm.nih.gov/pubmed/25520665
http://dx.doi.org/10.3389/fphys.2014.00461

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