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Length-dependent changes in contractile dynamics are blunted due to cardiac myosin binding protein-C ablation
Enhanced cardiac contractile function with increased sarcomere length (SL) is, in part, mediated by a decrease in the radial distance between myosin heads and actin. The radial disposition of myosin heads relative to actin is modulated by cardiac myosin binding protein-C (cMyBP-C), suggesting that c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251301/ https://www.ncbi.nlm.nih.gov/pubmed/25520665 http://dx.doi.org/10.3389/fphys.2014.00461 |