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Plasmodium attenuation: connecting the dots between early immune responses and malaria disease severity

Sterile attenuation of Plasmodium parasites at the liver-stage either by irradiation or genetic modification, or at the blood-stage by chemoprophylaxis, has been shown to induce immune responses that can protect against subsequent wild-type infection. However, following certain interventions, parasi...

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Detalles Bibliográficos
Autores principales: Fernandes, Priyanka, Frank, Roland, Lewis, Matthew D., Mueller, Ann-Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251431/
https://www.ncbi.nlm.nih.gov/pubmed/25520710
http://dx.doi.org/10.3389/fmicb.2014.00658