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Plasmodium attenuation: connecting the dots between early immune responses and malaria disease severity
Sterile attenuation of Plasmodium parasites at the liver-stage either by irradiation or genetic modification, or at the blood-stage by chemoprophylaxis, has been shown to induce immune responses that can protect against subsequent wild-type infection. However, following certain interventions, parasi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251431/ https://www.ncbi.nlm.nih.gov/pubmed/25520710 http://dx.doi.org/10.3389/fmicb.2014.00658 |