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Aberrant Methylation of PCDH8 is a Potential Prognostic Biomarker for Patients with Clear Cell Renal Cell Carcinoma

BACKGROUND: PCDH8 is a tumor suppressor that regulates cell adhesin, proliferation, and migration. It is often inactivated by aberrant promoter methylation in several human cancers, including clear cell renal cell carcinoma (CCRCC). The clinical significance of PCDH8 methylation in CCRCC remains unc...

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Detalles Bibliográficos
Autores principales: Lin, Ying-Li, Wang, Yan-Ling, Fu, Xing-Li, Ma, Jian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251547/
https://www.ncbi.nlm.nih.gov/pubmed/25416427
http://dx.doi.org/10.12659/MSM.892433