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BMP4 Increases the Expression of TRPC and Basal [Ca(2+)](i) via the p38MAPK and ERK1/2 Pathways Independent of BMPRII in PASMCs
Multiple abnormalities of bone morphogenetic protein (BMPs) signaling are implicated in the process of pulmonary arterial hypertension (PAH). BMP4 plays an important role during the process of pulmonary arterial remodeling and mutant of the principle BMP4 receptor, BMP receptors II (BMPRII), is foun...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251900/ https://www.ncbi.nlm.nih.gov/pubmed/25461595 http://dx.doi.org/10.1371/journal.pone.0112695 |