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HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage
BACKGROUND: Human immunodeficiency virus 1 and 2 (HIV-1 and HIV-2) use cellular receptors in distinct ways. Besides a more promiscuous usage of coreceptors by HIV-2 and a more frequent detection of CD4-independent HIV-2 isolates, we have previously identified two HIV-2 isolates (HIV-2(MIC97) and HIV...
Autores principales: | Santos-Costa, Quirina, Lopes, Maria Manuel, Calado, Marta, Azevedo-Pereira, José Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251929/ https://www.ncbi.nlm.nih.gov/pubmed/25421818 http://dx.doi.org/10.1186/s12977-014-0099-3 |
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