ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress

Unresolved replication intermediates can block the progression of replication forks and become converted into DNA lesions, hence exacerbating genomic instability. The p53-binding protein 1 (53BP1) forms nuclear bodies at sites of unrepaired DNA lesions to shield these regions against erosion, in a m...

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Detalles Bibliográficos
Autores principales: Schmidt, Luisa, Wiedner, Marc, Velimezi, Georgia, Prochazkova, Jana, Owusu, Michel, Bauer, Sabine, Loizou, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251980/
https://www.ncbi.nlm.nih.gov/pubmed/25262557
http://dx.doi.org/10.1016/j.dnarep.2014.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251980/
https://www.ncbi.nlm.nih.gov/pubmed/25262557
http://dx.doi.org/10.1016/j.dnarep.2014.09.001

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