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Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation

Response regulators are proteins that undergo transient phosphorylation, connecting specific signals to adaptive responses. Remarkably, the molecular mechanism of response regulator activation remains elusive, largely because of the scarcity of structural data on multidomain response regulators and...

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Detalles Bibliográficos
Autores principales: Trajtenberg, Felipe, Albanesi, Daniela, Ruétalo, Natalia, Botti, Horacio, Mechaly, Ariel E., Nieves, Marcos, Aguilar, Pablo S., Cybulski, Larisa, Larrieux, Nicole, de Mendoza, Diego, Buschiazzo, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251995/
https://www.ncbi.nlm.nih.gov/pubmed/25406381
http://dx.doi.org/10.1128/mBio.02105-14